Anadys Pharmaceuticals, Inc. To Be Added To The NASDAQ Biotechnology Index (NBI)

SAN DIEGO, Nov. 15 /PRNewswire-FirstCall/ -- Anadys Pharmaceuticals, Inc. announced today that the Nasdaq Stock Market, Inc. (NASDAQ) will add Anadys to the NASDAQ Biotechnology Index, following results of the semi-annual re-ranking of the NASDAQ Biotechnology Index (NBI). The re-ranking becomes effective when the market opens on Monday, November 21, 2005.

"We are very proud to be included in this select group of biopharmaceutical companies," said Kleanthis G. Xanthopoulos, Ph.D., Anadys' President and Chief Executive Officer. "We especially wish to thank our dedicated employees for the contributions they have made during the past year."

Securities in the NBI must meet certain Index eligibility criteria including listing on the NASDAQ National Market and meeting minimum requirements for market value, average daily share volume and seasoning as a public company, according to the Nasdaq. The Index is ranked on a semi-annual basis in May and November.

About Anadys

Anadys Pharmaceuticals, Inc. is a biopharmaceutical company committed to advancing patient care by discovering, developing and commercializing novel small molecule medicines for the treatment of hepatitis C virus (HCV), hepatitis B virus (HBV) and other serious infections. The Company has core expertise in Toll-Like Receptor-based small molecule therapeutics and structure-based drug design coupled with medicinal chemistry. Anadys' clinical development programs include ANA975 for the treatment of HCV and HBV, and ANA380 for the treatment of HBV. In addition, Anadys' therapeutic platform is designed to advance a strong and continual pipeline of drug candidates into the clinic.

Safe Harbor Statement

Statements in this press release that are not strictly historical in nature constitute "forward-looking statements." Such statements include, but are not limited to, the reference to the inclusion of Anadys in the NASDAQ Biotechnology Index (NBI). Such forward-looking statements involve known and unknown risks, uncertainties and other factors, which may cause Anadys' actual results to be materially different from historical results or from any results expressed or implied by such forward-looking statements. In particular, the results of initial clinical trials may not be predictive of future results, and Anadys cannot provide any assurances that any of its product candidates will have favorable results in future clinical trials or receive regulatory approval. In addition, Anadys' results may be affected by risks related to the implementation of its collaboration with Novartis, competition from other biotechnology and pharmaceutical companies, its effectiveness at managing its financial resources, its ability to successfully develop and market products, the level of effort that its collaborative partners devote to development and commercialization of its product candidates, difficulties or delays in its clinical trials, difficulties or delays in manufacturing its clinical trials materials, the scope and validity of patent protection for its products, regulatory developments involving future products and its ability to obtain additional funding to support its operations. These and other factors that may cause actual results to differ are more fully discussed in the "Risk Factors" section of Anadys' Form 10-Q for the quarter ended September 30, 2005. All forward-looking statements are qualified in their entirety by this cautionary statement. Anadys is providing this information as of this date and does not undertake any obligation to update any forward-looking statements contained in this document as a result of new information, future events or otherwise.

Anadys Pharmaceuticals, Inc.

CONTACT: Vince Reardon, Sr. Director, Investor Relations and CorporateCommunications of Anadys Pharmaceuticals, Inc., +1-858-530-3653, or cell,+1-858-228-7624

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