AIMM Therapeutics' Pre-Fusion RSV Antibodies Facilitate Improved Approach to Vaccine Development
Published: Nov 04, 2013
AMSTERDAM--(BUSINESS WIRE)--AIMM Therapeutics B.V., a leading developer of a new generation of therapeutic antibodies, announced today that researchers have used the Company’s unique family of antibodies that neutralize respiratory syncytial virus (RSV) to engineer an improved vaccine against RSV. In a paper published in Science titled ‘Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus’1, a team of scientists from the Vaccine Research Center (VRC) at the U.S. National Institute of Allergy and Infectious Diseases describe how structural biology insight into how AIMM’s highly potent RSV antibodies work enabled them to engineer a vaccine immunogen able to trigger a response 40 times higher than needed to neutralize RSV infection.
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