AC Immune SA Provides Seven Updates On Its Pipeline And Technology At The Alzheimer's Association International Conference

Lausanne, Switzerland, July 10, 2017 - AC Immune SA (NASDAQ: ACIU), a Swiss-based, clinical stage biopharmaceutical company focused on neurodegenerative diseases, today announced that seven updates on the advancement of its in-house and partnered product candidates and technology platforms will be provided at the
Alzheimer's Association International Conference (AAIC 2017©). The conference is the largest international meeting dedicated to advancing dementia science and takes place in London, UK from July 15th to July 20th, 2017.

Program and Collaborator Presentations and Timing
Crenezumab /

Mathematical model of amyloid beta dynamics to assess target engagement of soluble amyloid beta oligomers by crenezumab in the Alzheimer's disease brain
Poster - July 16 / 9:30 - 16:15 (S8, P109) Safety and tolerability of crenezumab in mild-to-moderate AD patients treated with escalating doses for up to 25 months
Oral presentation - July 17 / 17:30 - 17:45 (N10 )
anti-Tau antibody /

Changes in Tau protein landscape during Alzheimer's disease progression
Poster - July 19 / 9:30 - 16:15 (S8) A Phase 1 Study to evaluate the safety and tolerability of RO7105705 in healthy volunteers and patients with mild-to-moderate AD
Oral Presentation - July 17 / 16:45 - 17:00 (N10, P99)
Tau-PET imaging agent /

First in human PET studies with the next generation Tau agent 18F-PI-2620 in Alzheimer's disease, progressive supranuclear palsy and controls
Oral Presentation - July 15 / 10:00 - 10:15 (S10-C) Preclinical characterization of PI-2620, a novel Tau-PET-tracer for detection of Tau in AD and other Tauopathies
Poster - July 15 / 12:15 - 13:30 (S9, P192) Preclinical Characterization of PI-2620, a Novel Tau PET Tracer for detection of Tau in AD and other Tauopathies
Poster - July 17 / 9:30- 16:15 (S8, P381)
AC Immune vaccine technology

Development of highly sensitive MSD assays for the detection of anti-amyloid beta monomer and oligomer-specific antibodies in human serum
Poster - July 18 / 9:30-16:15 (S8, P67)

About AC Immune
AC Immune is a clinical stage Swiss-based biopharmaceutical company focused on neurodegenerative diseases with four product candidates in clinical trials. The Company designs, discovers and develops therapeutic and diagnostic products intended to prevent and modify diseases caused by misfolding proteins. AC Immune's two proprietary technology platforms create antibodies, small molecules and vaccines designed to address a broad spectrum of neurodegenerative indications, such as Alzheimer's disease. The Company's pipeline features seven therapeutic and three diagnostic product candidates. The most advanced of these is crenezumab, an anti-Abeta antibody in phase 3 clinical studies that is being advanced by the collaboration partner Genentech, Inc., a wholly owned subsidiary of Roche. Other business partners include Biogen, Janssen Pharmaceuticals, Nestlé Institute of Health Sciences, Piramal Imaging and Essex Bio-Technology.

Forward looking statements
This press release contains statements that constitute "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements are statements other than historical fact and may include statements that address future operating, financial or business performance or AC Immune's strategies or expectations. In some cases, you can identify these statements by forward-looking words such as "may," "might," "will," "should," "expects," "plans," "anticipates," "believes," "estimates," "predicts," "projects," "potential," "outlook" or "continue," and other comparable terminology. Forward-looking statements are based on management's current expectations and beliefs and involve significant risks and uncertainties that could cause actual results, developments and business decisions to differ materially from those contemplated by these statements. These risks and uncertainties include those described under the captions "Item 3. Key Information-Risk Factors" and "Item 5. Operating and Financial Review and Prospects" in AC Immune's Annual Report on Form 20-F and other filings with the Securities and Exchange Commission. Forward-looking statements speak only as of the date they are made, and AC Immune does not undertake any obligation to update them in light of new information, future developments or otherwise, except as may be required under applicable law. All forward-looking statements are qualified in their entirety by this cautionary statement.

For further information please contact:

Prof. Andrea Pfeifer
Chief Executive Officer
Phone: +41 21 345 91 21
Eva Schier
Corporate Communications Manager
Phone: +41 21 345 91 34
Mobile: +41 79 926 66 03

Nick Miles/Toomas Kull
Cabinet Privé de Conseils s.a.
Phone: +41 22 552 46 46

In the US
Ted Agne
The Communications Strategy Group Inc.
Phone: +1 781 631 3117


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