Shire Delivers Record Quarterly Revenues And Non GAAP Diluted Earnings Per ADS Up 42%.

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Increases Non GAAP diluted earnings per ADS guidance to low-to-mid thirty percent growth in 2014. July 18, 2014 – Shire (LSE: SHP, NASDAQ: SHPG) announces unaudited results for the three months to June 30, 2014.

            Financial Highlights                                         Q2 2014    Growth(1)
            Product sales                                         $1,470 million      +22%(2)
            Total revenues                                        $1,502 million      +20%
            Non GAAP operating income                               $630 million      +32%
            US GAAP operating income from continuing operations     $338 million      -14%
            Non GAAP EBITDA margin (excluding royalties & other
            revenues)(3)                                                     44%       n/a
            US GAAP net income margin(4)                                     35%       n/a
            Non GAAP diluted earnings per ADS                              $2.67      +42%
            US GAAP diluted earnings per ADS                               $2.66      +96%
            Non GAAP cash generation                                $659 million      +76%
            Non GAAP free cash flow                                 $830 million     +245%
            US GAAP net cash provided by operating activities       $834 million     +223%

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