Perceptive Instruments: Accuracy Of Comet Measurements In Image Analysis Systems

If you are scoring comets using image analysis, you will want to be confident that the results you are getting are accurate. Comet Assay IV from Perceptive Instruments has a unique scoring method that has been validated both in-house and by many of the world’s leading pharmaceutical organisations and CROs.

As part of the JaCVAM initiative to validate the in vivo and in vitro comet assays, Comet Assay IV is currently used by laboratories in Japan, Europe and the USA. The ultimate aim of this initiative is to work towards the introduction of an OECD guideline for the assay. For these laboratories, the accuracy of data gathered from our systems is of paramount importance.

As an ISO9001:2008 approved company, we develop and test our software in accordance with strict quality guidelines. Our own in-house validation exercises were performed on real and artificially generated comet images. Every attribute of each generated image was known in advance so the accuracy of any measurements obtained could be verified exactly. Comet Assay IV is not just accurate – its single-click scoring system is also extremely fast, with users typically scoring 50 cells within 2 minutes.

About Perceptive Instruments

Perceptive Instruments Ltd. (http://www.perceptive.co.uk) develops, manufactures and supplies image analysis and data processing solutions for many areas of scientific research and industry. Our products are used primarily in the pharmaceutical & health care industries, as well as environmental monitoring, food and manufacturing industries. We have established an enviable reputation based upon our willingness and ability to completely satisfy our clients’ needs. We provide standard 'off the shelf' systems and customised solutions based on current or novel technologies. Examples of special solutions include systems for antibiotic testing, vaccine development and robot vision.

Our Products

Comet Assay IV

Comet Assay IV is an interactive live video-based system for scoring cells subjected to the single cell gel electrophoresis technique (comet assay). The system is the very latest in a highly successful series of comet assay scoring systems from Perceptive Instruments that have evolved and developed since the release of our first system in 1992.

Sorcerer Colony Counter

Sorcerer provides instant, accurate plate counting for microbial and mammalian colonies. It is ideal for laboratories engaged in drug development and production, food and milk testing, environmental monitoring and public health.

Ames Study Manager

The Ames Study Manager is a study management and reporting system for Ames testing. Together with the Sorcerer automatic colony counter it provides a complete solution for regulatory and non-regulatory safety assessment.

SpeckCheck 2

SpeckCheck 2 is the advanced scanner based system for automatic detection and analysis of dirt and other contaminants in pulp and paper.

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