Foster Delivery Science Receives Grant From University of Connecticut to Develop Processes for Oral Dose Drug Delivery
Published: Mar 25, 2013
Many newly discovered pharmaceutical ingredients are poorly water soluble and result in low absorption rates in the body. Foster’s hot melt extrusion technology enhances bioavailability through melt dispersion of active pharmaceutical ingredients in a polymer matrix. The resulting drug/polymer matrix is then ground into powder form and pressed into tablets.
Foster and University of Connecticut will collaborate to develop continuous injection molding of the tablets from the drug/polymer matrix form, eliminating the powder grinding process. In addition Foster and University of Connecticut intend to explore foaming technology to reduce density and increase porosity of the molded tablets in an effort to further enhance the body’s absorption of drugs.
“Roughly half of the new drugs discovered are poorly soluble and require special processing, such as hot melt extrusion, for drug delivery dose forms,” said Tony Listro, Managing Director at Foster Delivery Science. “By combining our expertise in hot melt extrusion and the polymer processing resources at University of Connecticut we believe we can make meaningful advancements in manufacturing and performance of formulations involving poorly water soluble drugs.”
For more information, please visit www.deliveryscience.com