Popular Drug For Chest Pain May Promote Blood Vessel Damage

Nitroglycerin -- a drug commonly prescribed for the treatment of chest pain in patients with heart conditions -- has the frustrating property that its beneficial effects are short-lived. Now, new research conducted by a German group and Howard Hughes Medical Institute investigators at Duke University Medical Center reveals the cellular mechanism underlying the drug's lost efficacy and raises additional concern about its potential to cause long-term injury.

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