Next Generation Nanosuspension Processing for the Delivery of Non-Soluble Drugs, Microfluidics International Corporation
Published: Aug 15, 2008
AZNano -- Roughly half of all new drugs in development are poorly soluble and often associated with low bioavailability. Among the most promising solutions to this challenge are nanosuspensions, defined as a colloidal dispersion of submicron pure drug particles that are stabilized by surfactants. The small particle size provides increased surface area which can significantly improve bioavailability. Additionally, nanosuspensions can be formulated to deliver high concentrations of active pharmaceutical ingredients (API), overcoming the dosage limitations of other nanoparticles formulations like emulsions and liposomes.