Johns Hopkins University Epilepsy Study Is First Researchkit App To Use Apple Watch

EpiWatch is an epilepsy research study that monitors seizure symptoms with Apple Watch to improve seizure detection, improve medication adherence and enhance quality of life for those who suffer from seizures.

BALTIMORE--(BUSINESS WIRE)--Today, Johns Hopkins researchers introduced EpiWatch, designed to use Apple Watch to collect patient data through the open source ResearchKit framework designed by Apple. The app, which runs on Apple Watch and iPhone, collects data from patients with epilepsy before, during and after their seizures.

“The app also provides helpful tracking of seizures, prescription medication use and drug side effects — activities that are important in helping patients manage their condition.”

Over 2.5 million people are living with epilepsy in the United States. The data gathered by the app, including physiological changes, altered responsiveness and other characteristics of recurrent seizures, will be used by researchers to better understand epilepsy and to develop new methods for monitoring and managing the disease and the role of technology.

“Physicians often ask patients to record their seizures. But that can be hard, especially when a patient loses consciousness. EpiWatch collects data that help researchers better understand epilepsy, while helping patients keep a more complete history of their seizures,” says Gregory Krauss, M.D., professor of neurology at the Johns Hopkins University School of Medicine. “The app also provides helpful tracking of seizures, prescription medication use and drug side effects — activities that are important in helping patients manage their condition.”

Johns Hopkins’ EpiWatch modules enable research participants to complete an interactive, informed consent; track their seizures in real time, including prompts on the Apple Watch testing awareness; and answer research surveys and other tasks. Users can review their data and compare their symptoms to others in their demographic with similar seizures.

The back-end data solution is being provided by Acuma Health, a division of Smart Monitor, via a secure health informatics platform that protects patient information and provides custom analytics dashboards to researchers.

The app’s journaling function prompts users to answer a series of questions daily:

  • Have you had a seizure today? If so, what type of seizure was it?
  • Did you take your medication? If not, why not?

Epilepsy is a disorder of the brain in which seizures, caused by abnormal neural activity, disrupt normal brain function. Seizures can vary in their type and severity, sometimes causing convulsions and other abnormal movements, confusion, or loss of consciousness. People with uncontrolled seizures may experience impacts on their independence and quality of life.

“Many patients have a brief lapse of awareness during their seizures that may not be apparent to them or to others around them,” says Nathan E. Crone, M.D., associate professor of neurology at the Johns Hopkins University School of Medicine. “EpiWatch allows patients to find out for themselves if this is a problem so they can get more help.”

EpiWatch is most appropriate for patients with epilepsy who may experience an “aura” that signals an oncoming seizure. When this warning symptom occurs, the user — or a caregiver — can tap an icon on the watch face to activate the app. The app then starts recording heart rate and movements. The app also requests patient participation in a specialized memory game to evaluate patient responsiveness during the seizure. It is the first medical research app to include such a cognitive test.

Krauss and Crone have been working with developers at THREAD Research to build EpiWatch. The app makes use of many of the Apple Watch sensors — such as the accelerometer, which detects movements, and the gyroscope, which determines orientation in space — to measure and record movements and falls during seizures. The app also uses Apple Watch’s heart rate monitor, since heart rate can rise significantly during seizures.

Krauss expects that, after a year or two of data collection, Johns Hopkins will be able to develop an app that can detect most seizure types and generate an alert to notify caregivers and emergency personnel, if needed. This could not only be potentially lifesaving, but also allow people with epilepsy to have more freedom, says Krauss.

“We foresee the app giving some parents the confidence to allow their children to play on their own,” Krauss says. “For some adults, using it might allow them, for the first time, to live safely alone.”

EpiWatch is available to download for free from the App Store. For more information, visit

Johns Hopkins Medicine (JHM), headquartered in Baltimore, Maryland, is a $7.7 billion integrated global health enterprise and one of the leading academic health care systems in the United States. JHM unites physicians and scientists of the Johns Hopkins University School of Medicine with the organizations, health professionals and facilities of The Johns Hopkins Hospital and Health System. JHM's vision, “Together, we will deliver the promise of medicine,” is supported by its mission to improve the health of the community and the world by setting the standard of excellence in medical education, research and clinical care. Diverse and inclusive, JHM educates medical students, scientists, health care professionals and the public; conducts biomedical research; and provides patient-centered medicine to prevent, diagnose and treat human illness. JHM operates six academic and community hospitals, four suburban health care and surgery centers, and more than 39 primary and specialty care outpatient sites under the umbrella of Johns Hopkins Community Physicians. JHM extends health care into the community and globally through Johns Hopkins Home Care Group, Johns Hopkins Medicine International and Johns Hopkins HealthCare. The Johns Hopkins Hospital, opened in 1889, has been ranked number one in the nation by U.S. News & World Report for 22 years of the survey’s 26-year history. For more information about Johns Hopkins Medicine, its research, education and clinical programs, and for the latest health, science and research news, visit


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