How Celgene Has Led bluebird bio Into A Crowded Field

Published: Aug 31, 2017

- Bluebird bio's first love was gene therapy for inherited diseases affecting children; cerebral adrenoleukodystrophy, beta-thalassemia, and sickle cell anemia. Lenti-D and Lentiglobin were the lead product candidates.

- Bluebird partnered with Celgene; then Celgene seduced bluebird into changing its lead product candidate to a CAR-T for the myeloma BCMA (B- Cell Maturation Antigen).

- BCMA has attracted a crowd that includes Juno and some heavy-hitters like Novartis and Gilead's Kite.

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