Gut Microbe Battles Obesity, Catholic University of Leuven Study

Published: May 15, 2013

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Akkermansia muciniphila is one of the many microbes that live in our intestines. This bacterium, which feeds on the intestine's mucus lining, comprises between 3 and 5 percent of the gut microbes of healthy mammals. There is an inverse correlation between body weight and abundance of A. muciniphila in mice and humans. In a paper published in the Proceedings of the National Academy of Sciences, Patrice Cani of the Catholic University of Louvain in Belgium and his colleagues reveal that levels of this bacterium are very low in mice genetically predisposed to obesity. Restoring Akkermansia to normal levels leads to fat reduction and reduced insulin resistance.

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