Genetic Flaw Triggers Liver Cancer, Diabetes In Males, University of Michigan Study

Published: Dec 10, 2013

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A genetic deficiency in males can set off the development of one of the most common types of liver cancer and forms of diabetes, according to research with mice. The new study, published in the journal Cancer Cell, shows that when the NCOA5 gene, present in both men and women, is altered to a deficient level in male mice, a spontaneous reaction occurs that produces cells that can lead to hepatocellular carcinoma. The type of liver cancer is two-to-four times more prevalent in men than women.

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