Electroporation Instruments Market: Progress in Gene Editing Techniques to Propel Market Growth
Electroporation Instruments Market: Introduction
According to the report, the global electroporation instruments market was valued at ~US$ 126 Mn in 2019 and is projected to reach ~US$ 244 Mn by 2030, expanding at a CAGR of ~6% from 2020 to 2030. The electroporation technique involves exposure of cell membranes to high-intensity electric pulses that cause a temporary destabilization in certain areas of the cell. During this transient destabilization event, the cell membrane becomes highly permeable and allows the entry of various exogenous molecules, including the DNA. Electroporation is an easy, non-chemical technique that yields high transformation efficiencies in various cell types. This technique does not alter target cell morphology and functions; however, the technique can cause cell death if transfection is not carried out under optimum conditions.
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Technological Advancements to Boost Adoption of Electroporation for Treatment of Internal Tumor
Technological advancements have led to the efficient use of electroporation in the treatment of internal tumor. Electrochemotherapy is considered highly effective in the treatment of cutaneous and subcutaneous tumor. Features of the electroporation technique, such as high specificity for targeting cancer cells and high degree for localization of treatment result in better treatment of internal tumors. Advancements in the electroporation technology present better treatment option of liver and bone metastases, brain tumors, soft tissue sarcomas, and colorectal and esophageal tumors. Safe performance of electrochemotherpay in the treatment of internal tumors would be defined by non-interference with the heart’s electrical activity. The complete removal internal tumors includes positioning the electrode accurately to extend the electroporation in all tumor cells and to avoid damaging the healthy tissue or organs in the vicinity.
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Total Electroporation System to Gain Significant Market Share
In terms of product, the global electroporation instruments market has been segmented into total electroporation system, eukaryotic electroporation system, and microbial electroporation system. Increase in the burden of diseases across the globe has prompted various healthcare organizations to focus on drug discovery and drug development. These studies require application of experimental drugs on human and other eukaryotic cells to study their mechanism of action and their safety profile. Rise in demand for multifaceted devices that can be used for all types of cell studies leading to overall cost-effectiveness is anticipated to drive the total electroporation system during the forecast period.
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Bio-Medical Research to be Highly Lucrative
Based on application, the global electroporation instruments market has been classified into bio-medical research, therapeutic delivery, and protein production. The bio-medical research segment has been further sub-segmented into transgenic models, cancer research, gene and protein expression studies, and cell based microarrays for drug discovery and development. The therapeutic delivery segment has been further split into biotherapeutics, and electro-chemotherapy and electro-immunotherapy. The bio-medical research segment is likely to maintain its dominance during the forecast period. The segment is expected to expand significantly over the next few years due to increase in applications of electroporation in microbiology, oncology, surgery, biochemistry, public health, and other non-communicable diseases.
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North America to Dominate Global Market
In terms of region, the global electroporation instruments market has been divided into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominated the global electroporation instruments market in 2019, followed by Europe. Rise in prevalence of cancer and autoimmune diseases in North America boosted the transfection technology market. Biotherapeutic drugs are highly preferred for the treatment of cancer and autoimmune diseases. Increase in usage of these drugs is estimated to fuel the demand for transfection, as transfection is extensively employed for the production of biotherapeutic drugs.
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Major players operating in the global electroporation instruments market are BEX Co. Ltd., Celetrix LLC, Merck KGaA, Eppendorf AG, Harvard Bioscience Inc. (BTX), Thermo Fisher Scientific, Inc., Bio-Rad Laboratories, MaxCyte Inc., Lonza Group, and Mirus Bio LLC.
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