Mathematical Modeling Offers New Approaches To Fight Dual-Resistant Hospital Infections

BOSTON – A mathematical model that looks at different strategies for curbing hospital-acquired infections suggests that antimicrobial cycling and patient isolation may be effective approaches when patients are harboring dual-resistant bacteria. In an era of “superbugs,” such as methicillin-resistant Staphylococcus aureas (MRSA), and an increasing public awareness and concern over bacterial infections, this type of modeling, if used to develop policies and treatment protocols, may reduce dual drug-resistant infections in hospitals. The model’s results will be presented by Carlos Castillo-Chavez, an Arizona State University Regents’ Professor on Feb. 17 at the American Association for the Advancement of Science annual meeting. Castillo-Chavez will be honored at the meeting with the 2007 AAAS Mentor Award for his efforts to help underrepresented students earn doctoral degrees in the sciences.

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