Antibiotic Linked to Serious Bleeding Condition

The antibiotic vancomycin often used in intensive care units is considered the drug of choice for the treatment of staphylococci (staph) infections that are resistant to most other antibiotics. Researchers at the Medical College of Wisconsin in Milwaukee and the BloodCenter of Wisconsin's Blood Research Institute have linked vancomycin to an abnormal decrease in blood platelet count, a condition called thrombocytopenia. If accompanied by uncontrollable bleeding, thrombocytopenia can be fatal. The study led by Annette Von Drygalski, M.D., third year internal medicine resident, and Richard H. Aster M.D., professor of medicine at the Medical College, and senior investigator at the Blood Research Institute, will appear in the March 1, 2007, edition of New England Journal of Medicine.

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