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Asuragen, Inc. And Labceutics Report Results From Pan European Quality Assurance-Modeled Study On Standardization Of BCR-ABL1 Monitoring For CML Patients


9/4/2014 11:02:06 AM

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AUSTIN, Texas & BELFAST, United Kingdom--(BUSINESS WIRE)--Asuragen, a molecular diagnostics company using genomics to drive better patient management, and Labceutics, the leading global personalized medicine laboratory network, announced today the publication of the results from the first international, multi-center quality assurance study on the standardization of BCR-ABL1 quantitative measurements on the International Scale (IS). The double-blinded study assessed the variability of BCR-ABL1 testing by quantitative reverse transcription PCR (RT-qPCR) across 15 clinical laboratories performing routine monitoring of chronic myeloid leukemia (CML) patients treated with tyrosine kinase inhibitors (TKIs) in five European countries. The data demonstrate that the use of secondary IS reference materials anchored to the primary IS reference standards of the World Health Organization, the ARQ ISTM Calibrator Panels, can improve the precision and accuracy of BCR-ABL1 testing. The study results were initially reported at the 15th International Conference on CML organized by the European School of Haematology and the International Chronic Myeloid Leukemia Foundation in Estoril, Portugal, and were published by the College of American Pathologists in Archives of Pathology & Laboratory Medicine.

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