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Advanced Cancer Therapeutics Enters Phase 1 Human Clinical Trials With First-in-Class Anti-Cancer Drug Candidate


6/4/2014 9:05:45 AM

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LOUISVILLE, Ky., June 4, 2014 (GLOBE NEWSWIRE) -- Advanced Cancer Therapeutics (ACT), a privately held company dedicated to bringing new anti-cancer therapies to market, announced today that it has begun clinical trials of PFK-158, a small molecule therapeutic candidate that inactivates a novel cancer metabolism target never before examined in human clinical trials. The U.S. Food and Drug Administration (FDA) approved Phase 1 dose escalation study is evaluating the safety, tolerability and anti-tumor activity of PFK-158 in cancer patients with solid tumors such as melanoma, lung, colon, breast and pancreatic cancer.

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