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Curis, Inc. (CRIS) Announces U.S. Patent Issuance Covering CUDC-907 Composition-Of-Matter


4/30/2014 9:12:33 AM

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LEXINGTON, Mass., April 30, 2014 (GLOBE NEWSWIRE) -- Curis, Inc. (Nasdaq:CRIS), an oncology-focused company developing novel, targeted drug candidates for the treatment of human cancers, today announced the issuance of U.S. Patent No. 8,710,219 entitled "Phosphoinositide 3-kinase inhibitor with a zinc binding moiety" that covers composition-of-matter for CUDC-907, Curis' dual histone deacetylase (HDAC) and phosphoinositide 3-kinase (PI3K) inhibitor. This patent, along with related patents issued in June 2013 (U.S. Patent no. 8,461,157) and February 2013 (U.S. Patent No. 8,367,663), covers a broad range of proprietary chemical entities that target HDAC and PI3K enzymes, and in some instances mammalian target of rapamycin (mTOR), within a single molecule for the treatment of certain human diseases. CUDC-907 is being investigated in a Phase 1 study in patients with relapsed/ refractory lymphoma or multiple myeloma.

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