3/25/2014 9:12:37 AM
CAMBRIDGE, Mass., March 24, 2014 (GLOBE NEWSWIRE) -- Blueprint Medicines today announced that new data on its first-in-class isoform selective fibroblast growth factor receptor 4 (FGFR4) inhibitor will be presented during a late-breaking minisymposium at the 105th Annual Meeting of the American Association for Cancer Research (AACR) taking place April 5-9, 2014, in San Diego, California. The presentation by Blueprint's Chief Scientific Officer Christoph Lengauer, Ph.D., will include preclinical data examining the impact of isoform selective FGFR4 inhibition in hepatocellular carcinoma with amplification or overexpression of FGF19 (fibroblast growth factor 19). FGF19 is the ligand of FGFR4 and a genomic driver in hepatocellular carcinoma.
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