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Tumor Cells' Weird Appetites For Amino Acids Are Aeglea BioTherapeutics' Targets


2/19/2014 7:38:27 AM

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Researchers are always looking for the Achilles’ heel of cancer—some weakness in tumor cells that can be attacked by drugs while leaving normal cells unharmed. Austin, TX-based Aeglea BioTherapeutics is trying to exploit a vulnerability that might make it possible to starve certain cancers to death. In some tumors, the cells can no longer make one of the building blocks of proteins, an amino acid called arginine.

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