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Award Winning Ostendum Lab-On-A-Chip Nanodevices Are Produced With Scienion AG's sciFLEXARRAYER SX
1/27/2014 10:15:24 AM
Dortmund and Berlin, Germany, January 27, 2014: SCIENION AG today announced that Ostendum R&D B.V., a Dutch company focused on the development and production of fast, highly sensitive, portable, easy-to-use and cost-effective biosensors, is using SCIENION’s sciFLEXARRAYER to print their unique Lab-on-a-Chip nanodevices.
Ostendum has developed a proprietary technology for the Lab-on-chip nanodevices market which has been awarded a number of awards, most recently the 2013 Frost & Sullivan Award for Technology Innovation Leadership. The technology includes both novel Lab-on-a-Chip nanodevices and an integral optical detection platform.
“We were able to experience and see the advantages of SCIENION’s sciFLEXARRAYER technology at the laboratory of Dr. Aart van Amerongen of the Biomolecular Sensing & Diagnostics group of Wageningen UR (collaborative group conducting food research as a core area)”, says Ostendum’s CEO Dr. Paul H. J. Nederkoorn. “We came to the conclusion that the sciFLEXARRAYER non-contact dispenser would be the best solution to precisely and accurately spot antibodies onto our nanodevices. After further test runs with excellent results in SCIENION’s facilities, we opted for the SX model which enables us to complete any R&D processes and to scale up for production. This compact and fully-automated system will allow high throughput production of our chips. Furthermore it is suitable for our future activities in developing higher multiplexed chips, whereas we may increase the number of channels from currently four to up to eight channels per device.”
Analytes are bound specifically in the measurement channels on the chip:
After pre-coating the channels with specific antibodies, analytes (viruses or other antigens) bind specifically to complementary antibodies in the respective channels.
The change in the optical phase (detected by a CCD camera) compared to that of the reference channel is used to detect the presence of the analyte sought and furthermore, its precise concentration is calculated within minutes.
Dr. Holger Eickhoff, CEO of SCIENION AG, states: “With its fully portable Lab-on-a-Chip system Ostendum has developed a unique technology which offers tailor-made solutions for present needs in healthcare diagnostics as well as other areas such as food and water analytics or biological warfare testing. This portable point-of-care diagnostics technology for viruses and bacteria may play an important role in future control of epidemics or biohazards. Furthermore, point-of-care diagnostics of biomarkers will enable healthcare providers with vital information to act quickly and adequately. We are very happy that Ostendum decided for the sciFLEXARRAYER SX to produce their LOC nanodevices. I am looking forward to a productive collaboration with this innovative company.”
The potential of Ostendum’s technology for changing the healthcare landscape is also reflected by recent investments of two Dutch health insurers. In May 2013, the company raised venture capital from Achmea, the largest health insurer of the Netherlands, and from de Friesland Zorgverzekeraar.
Please meet us at: Molecular Med TRI-CON, February 10-12, 2014 in San Francisco, CA, USA; booth 522.
Register now for the 1st Sony DADC & SCIENION Symposium „Ideas at the point of commercialization“, March 31, 2014 in Salzburg, Austria. The agenda is available at www.scienion.com.
Ostendum is a group of companies that commercializes Lab-on-a-Chip optical biosensing nanodevices for detection of micro-organisms, biomarkers, (bio-) molecules and nano-particles. Ostendum develops and produces both the necessary hardware and software, including its own Lab-on-a-Chip system. Ostendum’s Lab-on-a-Chip interferometric nanotechnology is unique, being completely label-free, and extremely sensitive, being at least 100 times more sensitive than all currently available competing detection methods. The LOC devices do not only enable the detection of bacteria, viruses, yeasts, proteins and DNA molecules but also the determination of its concentration. Tests can be performed within minutes and everywhere, due to the portability of the system, contributing to faster analysis and savings on operational costs.
About SCIENION AG
SCIENION AG and its US subsidiary SCIENION US, Inc. provide systems and services for the contact-free printing of biological and chemical agents for diagnostics, pharmaceutics, veterinary, plant and food analytics and research. Addressing the dynamically increasing needs for miniaturization and multiplex analyses, SCIENION offers a unique technology portfolio that has been continuously expanded over one decade. SCIENION provides flexible solutions for research and development whereas solutions for production purposes are rather customized. Systems and software are characterized by their versatility, precision and robustness. The company is renowned specialist for ultra low volume liquid handling, particularly for the handling of precious and sensitive compounds of biological or chemical origin. SCIENION’s dispensers allow for contact-free and precise drop spotting in the pico- to micro-liter range and are optimally suited for microarray based analytics – such as for tests with DNA, oligonucleotides, peptides, proteins, antibodies, glycans or for dispensing cells onto various substrates. The company operates from two sites in Germany, Dortmund and Berlin, and has a subsidiary in New Jersey, USA.
Phone: +49 (0)30 - 6392 1700
Fax: +49 (0)30 - 6392 1701
Ostendum R&D B.V.
Dr. Paul H. J. Nederkoorn
De Veldmaat 10
Bldg. 46 / HTF-SEPA HI.222-224
P.O. Box 217
NL-7500 AE Enschede
Tel. +31 (0)53 20 30 063
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