Melbourne Australia; 17 April 2013 - Starpharma Holdings Ltd (ASX: SPL; OTCQX:
SPHRY) today announced it has been granted three new patents by the United States
Patent and Trademark Office (USPTO) which strengthen and expand the Company’s patent
estate for its drug delivery platform.
The patents provide “composition of matter” protection for Starpharma’s dendrimer
technologies for drug delivery out to 2029 in the United States, which is the world’s largest
pharmaceutical market for several important drug classes.
China’s patent office has also informed the Company that it has allowed a similarly broad,
drug delivery-related patent for Starpharma in this important Asian market. This fourth
patent, to expire in 2027, will be granted once an administrative process is complete.
“The granting of these patents adds to Starpharma’s considerable dendrimer intellectual
property portfolio and expands the Company’s patents on drug delivery-related applications,”
said Starpharma CEO Dr Jackie Fairley.
“They provide a firm footing for the commercialisation of our drug delivery technology, via
our internal programs and work with partners including some of the largest global
The patents offer broad and long-standing protection, and are in addition to other patent
filings which encompass the Company’s leading delivery candidate - a dendrimer-enhanced
version of the anti-cancer drug docetaxel (Taxotere®).
Dr Fairley also noted the granting of these patents coincides with growing interest in
nanomedicine by pharmaceutical companies, and a strong deal-making environment.
“In 2013 alone we have seen Pfizer, Amgen and Astellas Pharma each sign deals in the
nanomedicine space with the aim of progressing pre-clinical drug candidates to market.
The value of those three deals total almost $700 Million in upfront and potential royalty
payments, reflecting growing interest in this emerging and high-potential field of medicine.”
This increased activity is supported by industry estimates of the market for nanomedicinebased
oncology drugs growing from $5.5 Billion in 2011 to $12.7 Billion in 2016.
The new patents provide broad protection around the function of Starpharma’s dendrimers in
drug delivery. Dendrimer formulations of existing drugs offer the ability to create proprietary
products which have advantages such as improved drug efficacy, reduced toxicity, improved
solubility, extended drug half-life and targeting of pharmaceuticals to specific cells or tissues.
The patents are not limited by disease area or route of delivery, and apply to dendrimer
applications involving many classes of drugs such as small molecules, proteins, peptides
More information how Starpharma is applying this technology in its own pipeline can
be found at www.starpharma.com
Starpharma Holdings Limited (ASX:SPL, OTCQX:SPHRY), located in Melbourne Australia, is an ASX 300 company and is
a world leader in the development of dendrimer products for pharmaceutical, life science and other applications.
Starpharma’s underlying technology is built around dendrimers – a type of synthetic nanoscale polymer that is highly regular
in size and structure and well suited to pharmaceutical uses. Starpharma has three core development programs: VivaGel®
portfolio, drug delivery, and agrochemicals with the Company developing a number of products internally and others via
Starpharma’s lead product is VivaGel® (SPL7013 Gel), a gel-based formulation of a proprietary dendrimer. VivaGel® is
under clinical development for the treatment and prevention of bacterial vaginosis (BV) and also as a vaginal microbicide to
prevent the transmission of sexually transmitted infections including HIV and genital herpes. Starpharma has also signed
separate licence agreements with Ansell Limited (ASX:ANN) and Okamoto Industries Inc (Tokyo Stock Exchange) to market
a value-added, VivaGel®-coated condom. Ansell manufactures and sells leading condom brands worldwide, including
Lifestyles®, ZERO® and SKYN®. Okamoto is the market leader for condoms sold in Japan, the world’s second largest
In the wider pharmaceutical and life science fields, Starpharma has both partnered and internal programs in Drug Delivery.
Drug Delivery partners include GSK, Lilly and AstraZeneca. In its internal program Starpharma has announced significant
tumour-targeting results in its docetaxel (Taxotere®) program, with animal studies showing its dendrimer-enhanced version
of docetaxel to have significantly superior anti-cancer effects across a range of important cancer types including breast,
prostate, lung and ovarian tumour, when compared to Taxotere® (docetaxel).
In agrochemicals Starpharma has a series of partnerships with leading industry players including Nufarm (ASX:NUF) and
Makhteshim Agan as well as internal programs including an enhanced version of glyphosate (the active ingredient in
For Further Information:
Mob: +61 417 382 391
Mob: +61 407 25 00 88
Dr Jackie Fairley, Chief Executive Officer
+61 3 8532 2704
Ben Rogers, Company Secretary
Forward Looking Statements
This document contains certain forward-looking statements, relating to Starpharma’s business, which can be
identified by the use of forward-looking terminology such as “promising”, “plans”, “anticipated”, “will”, “project”,
“believe”, “forecast”, “expected”, “estimated”, “targeting”, “aiming”, “set to”, “potential”, “seeking to”, “goal”, “could
provide”, “intends”, “is being developed”, “could be”, “on track”, or similar expressions, or by express or implied
discussions regarding potential filings or marketing approvals, or potential future sales of product candidates.
Such forward-looking statements involve known and unknown risks, uncertainties and other factors that may
cause actual results to be materially different from any future results, performance or achievements expressed or
implied by such statements. There can be no assurance that any existing or future regulatory filings will satisfy the
FDA’s and other health authorities’ requirements regarding any one or more product candidates nor can there be
any assurance that such product candidates will be approved by any health authorities for sale in any market or
that they will reach any particular level of sales. In particular, management’s expectations regarding the approval
and commercialization of the product candidates could be affected by, among other things, unexpected clinical
trial results, including additional analysis of existing clinical data, and new clinical data; unexpected regulatory
actions or delays, or government regulation generally; our ability to obtain or maintain patent or other proprietary
intellectual property protection; competition in general; government, industry, and general public pricing pressures;
and additional factors that involve significant risks and uncertainties about our products, product candidates,
financial results and business prospects. Should one or more of these risks or uncertainties materialize, or should
underlying assumptions prove incorrect, actual results may vary materially from those described herein as
anticipated, believed, estimated or expected. Starpharma is providing this information as of the date of this
document and does not assume any obligation to update any forward-looking statements contained in this
document as a result of new information, future events or developments or otherwise.