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ScienceDaily (June 25, 2009) — New imaging research in the June 24 issue of The Journal of Neuroscience helps explain why sleep deprivation affects some people more than others. After staying awake all night, those who are genetically vulnerable to sleep loss showed reduced brain activity, while those who are genetically resilient showed expanded brain activity, the study found. The findings help explain individual differences in the ability to compensate for lack of sleep.