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Columbia University's New Study Reveals for First Time how BRCA1 Mutations Cause Breast Cancer  
12/9/2007 9:19:25 PM

NEW YORK (Dec. 9, 2007) – An international team of researchers led by Columbia University Medical Center’s Herbert Irving Comprehensive Cancer Center and Sweden’s Lund University has, for the first time, revealed how mutations in the BRCA1 gene lead to breast cancer. Findings show that one way BRCA1 mutations cause cancer is by knocking out a powerful tumor suppressor gene known as PTEN.
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