New 'Knock-Out' Gene Model Provides Molecular Clues to Breast Cancer  
9/6/2007 12:30:42 AM

Cincinnati—New insights into the role of estrogen receptor in mammary gland development may help scientists better understand the molecular origin of breast cancer, according to new research from the University of Cincinnati (UC). About a decade ago, U.S. scientists at the National Institutes of Health (NIH) developed a standard estrogen receptor (ER) gene knock-out mouse model to study the estrogen receptor’s role in human diseases.