Gene Deficiency is a Protective Barrier to Obesity, Mayo Clinic (Jobs) Study  
6/26/2007 12:01:23 PM

ROCHESTER, Minn. -- A search for the molecular clues of longevity has taken Mayo Clinic researchers down another path that could explain why some people who consume excessive calories don't gain weight. The study, which was done in laboratory mouse models, points to the absence of a gene called CD38. When absent, the gene prevented mice on high-fat diets from gaining weight, but when present, the mice became obese.