Board Director Purchases Shares in Amarin Pharmaceuticals, Inc.  
3/15/2007 1:23:41 PM

LONDON, March 15 /PRNewswire-FirstCall/ -- As required under applicable stock exchange regulations, Amarin Corporation plc ("Amarin" or "Company") announces that Dr Simon Kukes, a non-executive member of the Board of Directors of Amarin, made a market purchase of 285,000 American Depositary Shares ("ADSs") of Amarin on March 14, 2007 at an average price per ADS of $2.40. Following this purchase and the other purchase of 500,000 ADSs by Dr Kukes earlier this week announced on March 13, 2007, Dr Kukes now holds 8,274,212 ADSs of Amarin which represent 9.12% of the issued share capital of the Company.

About Amarin

Amarin is committed to improving the lives of patients suffering from diseases of the central nervous system. Our goal is to be a leader in the research, development and commercialization of novel drugs that address unmet patient needs.

Amarin has a late-stage drug development pipeline. Miraxion, Amarin's lead development compound, is in phase III development for Huntington's disease ("HD"), phase II development for depressive disorders and entering Phase IIa development for Parkinson's disease. Amarin's core development pipeline also includes the global rights to an oral formulation of apomorphine for treating patients with advanced Parkinson's disease and a nasal formulation of lorazepam for treating emergency seizures.

Miraxion for HD is being developed under a Special Protocol Assessment agreed with the US Food and Drug Administration ("FDA"), has been granted Fast Track designation by the FDA and has received Orphan Drug designation in the US and Europe.

Amarin has its primary stock market listing in the US on NASDAQ ("AMRN") and secondary listings in the UK and Ireland on AIM ("AMRN") and IEX ("H2E") respectively.

For press releases and other corporate information, visit the Amarin website at Information on our website does not form part of this press release.

Amarin Corporation Plc

CONTACT: Contacts: Amarin, +44-(0)-207-907-2442, Rick Stewart, ChiefExecutive Officer, Alan Cooke, Chief Financial Officer,, Investors: Lippert/Heilshorn &Associates, Inc., +1-212-838-3777, Kim Golodetz, Anne Marie Fields, Media:Powerscourt, +44-(0)-207-236-5615, Rory Godson, Victoria Brough