MacroGenics, Inc. (MGNX) Presents Pre-Clinical Data On Inhibition Of Autoimmune Diseases With DART Candidate MGD010 At IMMUNOLOGY 2014  
5/6/2014 9:37:55 AM

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ROCKVILLE, Md., May 5, 2014 (GLOBE NEWSWIRE) -- MacroGenics, Inc. (Nasdaq:MGNX), a clinical-stage biopharmaceutical company focused on discovering and identifying innovative monoclonal antibody-based therapeutics for the treatment of cancer and autoimmune diseases, today announced the presentation of pre-clinical data on MGD010, a bi-specific Dual-Affinity Re-targeting (DART®) protein, demonstrating its ability to inhibit B-cell activation without B-cell depletion, which could provide a novel treatment option for patients with autoimmune disorders. MGD010 also was shown to inhibit the development of graft-versus-host disease in a humanized murine model, a system amenable to ascertain the activity of immunomodulatory intervention. These data were presented at IMMUNOLOGY 2014, the American Association of Immunologists' Annual Meeting, in Pittsburgh, PA.

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