Pacific Biosciences Introduces New Chemistry With Longer Read Lengths to Detect Novel Features in DNA Sequence and Advance Genome Studies of Large Organisms
10/3/2013 10:05:32 AM
MENLO PARK, Calif., Oct. 3, 2013 (GLOBE NEWSWIRE) -- Pacific Biosciences of California, Inc. (Nasdaq:PACB), provider of the PacBio® RS II DNA Sequencing System, today announced significant new product enhancements to support researchers working on complex genome projects. The new P5 polymerase and C3 chemistry combination (P5-C3) extends the industry-leading sequence read lengths to an average of approximately 8,500 bases, with the longest reads exceeding 30,000 bases. A key feature of this performance enhancement is the inclusion of new photo-protected dyes, used to distinguish the four DNA bases using four colors of fluorescence. These photo-protected dyes shield the P5 polymerase from laser-induced damage, allowing the polymerase to provide extremely long sequencing reads.
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