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The Michael J. Fox Foundation Launches $10-million Edmond J. Safra Core Programs for PD Research  
6/5/2013 9:33:27 AM

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NEW YORK, June 4, 2013 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation for Parkinson's Research (MJFF) has committed up to $10 million to its next funding round for the Edmond J. Safra Core Programs for PD Research to prioritize research toward transformative treatments and a cure for Parkinson's disease (PD).

The Edmond J. Safra Core Programs include the Rapid Response Innovation Awards, focused on breakthrough ideas, Target Validation, which supports testing of biological targets with potential to become the new PD drugs of the future, and the Therapeutic Pipeline Program, designed to support critical pre-clinical and clinical development of promising Parkinson's therapies,

"We have never felt more optimistic that working together, we can reach our end goal of developing improved treatments and a cure," said Todd Sherer, PhD, CEO of MJFF. "The Edmond J. Safra Core Programs for PD Research provide consistent, significant funding for investigator-initiated projects that can help us achieve our goal sooner rather than later."

To learn more about how to apply, researchers should visit www.michaeljfox.org/research/apply-for-grant.html. Target Validation and Therapeutic Pipeline Program initial applications are due October 30. Rapid Response Innovation Awards proposals are accepted on a rolling basis with funding decisions made within six weeks of submission.

A brief description of the three launching programs follows:

Rapid Response Innovation Awards: The Rapid Response Innovation Awards (RRIA) program supports high-risk, high-reward projects with little-to-no existing preliminary data, but with potential to significantly impact our understanding of Parkinson's disease. Moreover, this program is well-suited for early exploratory studies that may open the field up to new targets or pathways that may ultimately feed the early drug development pipeline for a treatment of PD.

Target Validation: The Target Validation program supports work seeking to determine if manipulating a novel biological target has impact in a PD-relevant pre-clinical modelan essential early step to the development of potentially promising therapies.

Therapeutic Pipeline Program: The Therapeutic Pipeline Program is open to industry and academic investigators working at either pre-clinical or clinical stages of drug and therapeutic development. Proposals must focus on a treatment strategy with clear potential for PD and have a well-defined plan for moving toward clinical utility for patients. Both novel approaches as well as repositioning of approved or clinically safe therapies from other non-PD indications are of interest. Applicants are asked to justify the therapeutic targets relevant for PD, provide details of the therapeutic strategy, and clearly identify any suboptimal properties of their therapeutic strategy.

The Edmond J. Safra Core Programs for PD Research are supported in part by longtime MJFF friend Mrs. Lily Safra in honor of her late husband. Mrs. Safra has served on MJFF's Board of Directors since 2001 and is chairwoman of The Edmond J. Safra Philanthropic Foundation.

In addition to these new programs, six other programs are currently open and accepting applications. The complete list and applications for funding are also available at the Foundation's Web site.

About The Michael J. Fox Foundation for Parkinson's Research

As the world's largest private funder of Parkinson's research, The Michael J. Fox Foundation is dedicated to accelerating a cure for Parkinson's disease and improved therapies for those living with the condition today. The Foundation pursues its goals through an aggressively funded, highly targeted research program coupled with active global engagement of scientists, Parkinson's patients, business leaders, clinical trial participants, donors and volunteers. In addition to funding more than $325 million in research to date, the Foundation has fundamentally altered the trajectory of progress toward a cure. Operating at the hub of worldwide Parkinson's research, the Foundation forges groundbreaking collaborations with industry leaders, academic scientists and government research funders; increases the flow of participants into Parkinson's disease clinical trials with its online tool, Fox Trial Finder; promotes Parkinson's awareness through high-profile advocacy, events and outreach; and coordinates the grassroots involvement of thousands of Team Fox members around the world.

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SOURCE The Michael J. Fox Foundation



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