Cold Spring Harbor Laboratory Scientists Determine Mechanism of One of the Most Powerful Tumor-Suppressor Proteins, Chd5
1/11/2013 7:33:30 AM
A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects. The findings, published online today in the journal Cell Reports, are important because Chd5 engages processes fundamental to cancer prevention. Conversely, when Chd5 is mutated or missing, an important door is opened to cancer initiation.