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Identifying the Molecular Causes of Vision Loss in Demyelinating Disease, University of Miami Study  
1/3/2013 7:43:45 AM

Demyelinating diseases, such as multiple sclerosis (MS), are frequently associated with the progressive loss of vision. The retinal nerve damage is thought to be caused by immune system-mediated inflammation; however, other demyelinating disorders, such as Pelizaeus-Merzbacher disease, do not involve the immune system, suggesting that there are other causes of retinal nerve damage. Deimination is a protein modification that is altered in patients with MS and PMD.
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