Idera Pharmaceuticals, Inc. (IDRA) Present New Data That Show Toll-like Receptor Antagonists Inhibit Inflammasome Activation and Suppress Induction of Interleukin 1 Beta in Autoimmune Disease Models  
10/30/2012 7:47:20 AM

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Idera Pharmaceuticals, Inc. (NASDAQ: IDRA) today announced new data from preclinical studies showing that selective inhibition of Toll-like Receptors (TLRs) 7, 8, and 9, which play a key role in inflammation and immunity, also resulted in inhibition of inflammasome activation and induction of Interleukin 1 beta (IL-1ß), a pro-inflammatory cytokine that has been shown to be involved in Behçet's disease, non-infectious uveitis, cardiovascular disease, and other auto-inflammatory diseases. The data were presented during the 8th Annual Meeting of the Oligonucleotide Therapeutics Society being held October 28-31, 2012 in Boston.