Breast Stem-Cell Research: Receptor Teamwork is Required and a New Pathway May be Involved, University of Wisconsin-Madison Study  
5/31/2012 7:41:42 AM

Breast-cancer researchers at the University of Wisconsin-Madison have found that two related receptors in a robust signaling pathway must work together as a team to maintain normal activity in mammary stem cells. Mammary stem cells produce various kinds of breast cell types. They may also drive the development and growth of malignant breast tumors. Published recently in the Journal of Biological Chemistry, the research also suggests that a new signaling pathway may be involved, a development that eventually could take cancer-drug manufacturers in a new direction