Porvair Filtration Group Ltd. Release: Chromatrap® Enriches Transcriptional Factor from Clinical Tissue  
3/23/2012 9:47:40 AM

March 23, 2012 -- Chromatrap® Pro-A, the novel solid-based matrix for chromatin immunoprecipitation assays (ChIP) has been successfully used by researchers to understand the role of CTCF, a transcription factor, in tumorigenesis in clinical tissue specimens.

A recent study by the School of Biological Sciences, University of Essex, used Chromatrap® Pro-A 1ml columns with gravity feed to assess the occupancy of various key regulators such as c-myc and ERG1 at CTCF target sites in the p14ARF and Bax promotor regions in clinical tissue samples. Excellent enrichment was achieved from the complex tissue samples and the Chromatrap® Pro-A 1ml columns proved easy-to-use with either gravity or vacuum for more rapid throughput.

Full details are available in a newly published Application Note. For a copy of the Application Note please visit or contact Porvair Filtration Group on +44-1489-864330 / +1-804-550-1600 / email

Porvair Filtration Group is an international leader in the development and supply of materials and products for filtration and separation applications. Their expertise in a wide range of media and the dedication of their design, manufacturing, sales, test and research teams ensure they are at the forefront of filtration technology, delivering world class performance to the Life Science, Aerospace, Defence, Nuclear, Energy, Chemical Process, Industrial Process, Water Treatment and Printing markets. With offices and manufacturing sites located in the UK, Europe and the USA combined with a world-wide network of market representatives and distributors, they pride themselves on their continuous innovation and research to meet global demands.