Zürich-Schlieren, Switzerland, May 16th, 2011 -- Franz Hefti is currently Chief Scientific Officer of Avid Radiopharmaceuticals (Philadelphia, US), a company pioneering the development of imaging agents for neurodegenerative diseases. After successfully completing Phase III clinical trials with the amyloid plaque imaging agent
Florbetapir, Avid Radiopharmaceuticals was acquired by Eli Lilly (Indianapolis, US) in 2010 for
an upfront of USD 300 million and up to USD 500 million in additional payments contingent
upon regulatory and commercial milestones. Previously, Franz Hefti was Executive Vice
President of Drug Development at the Genentech spin-out company Rinat Neuroscience
Corporation (San Francisco, US), where he brought antibody therapeutics for Alzheimer’s
disease and chronic pain from discovery research to clinical development, which led to the
acquisition of Rinat by Pfizer Inc. (New York, US) in 2006.
Before joining Rinat, Franz Hefti was Senior Vice President of Neuroscience Research at Merck
& Co (Whitehouse Station, US) and Director of the Neuroscience Research Department at
Genentech (San Francisco, US). Prior to starting his industrial career, Franz Hefti spent more
than a decade in academia as a Professor at the University of Southern California in Los
Angeles and Associate Professor at the University of Miami, where he carried out seminal
research on therapeutic applications of neurotrophic factors. Franz Hefti received his PhD from
the University of Zurich (Switzerland) and did his postdoctoral research at the Massachusetts
Institute of Technology (Boston, US) and the Max Planck Institute in Munich (Germany).
“Franz Hefti’s valuable knowledge in preclinical and clinical development of biologics and his
management experience in two very successful biotech companies will be great assets to
Covagen’s Board of Directors”, said Julian Bertschinger, Chief Executive Officer of Covagen.
Commenting on his nomination, Franz Hefti stated: “It is a pleasure and honor for me to serve
on the Board of Directors of Covagen. Based on its innovative Fynomer technology and its
recent exciting scientific discoveries, Covagen is poised to bring new treatment modalities to
patients suffering from severe chronic diseases.”
After having served for more than four years as Chairman and member of Covagen’s Board of
Directors, Dr. Rudolf Gygax will retire from this position. “Rudolf Gygax has been instrumental
for building Covagen”, said Julian Bertschinger, Chief Executive Officer of Covagen. “We thank
him very much for his valuable support and advice.”
For further details, please contact:
Covagen AG
Dr. Julian Bertschinger, CEO
Tel: +41 (0) 44 732 46 60
julian.bertschinger@covagen.com
About Covagen:
Covagen commercializes next generation protein drugs for the treatment of
inflammatory diseases and cancer by using its proprietary protein engineering technology,
which has been developed at ETH Zurich (Switzerland). Covagen's innovative platform
comprises a novel single domain protein scaffold, which - in analogy to antibodies - can be
engineered to yield high affinity binding proteins called Fynomers that can be used for
therapeutic applications. The possibility to create bispecific as well as multivalent Fynomers
and their favorable biophysical properties allow for treatment modalities that are difficult or
impossible to be exploited with antibodies.