Study Sheds Light on Cancer-Causing Gene Regulation, Beth Israel Deaconess Medical Center Study
8/18/2010 6:28:22 AM
EurekAlert! -- BOSTON – Researchers at Beth Israel Deaconess Medical Center (BIDMC) have uncovered the genes that regulate MDM2, an oncogene that, in turn, regulates the tumor suppressor protein p53. But instead of an on-off switch for MDM2, the team found what looks like a dimmer switch, suggesting a more complicated signaling pathway that is sensitive to a changing environment.