Tamoxifen May Worsen Breast Cancer, Cardiff University Study  
12/18/2008 8:57:44 AM

ScienceDaily (Dec. 18, 2008) — Tamoxifen may worsen breast cancer in a small subset of patients. Research published in BioMed Central's open access journal Breast Cancer Research suggests that in patients who show reduced or absent expression of the protein E-cadherin, commonly used anti-oestrogen drugs such as tamoxifen may promote more harmful cancer cell behaviour.