SRA / Scientist Discovery Research - San Diego, CA | Biospace
Get Our FREE Industry eNewsletter

SRA / Scientist Discovery Research

Regulus Therapeutics, Inc.

San Diego, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Bachelors Degree
Areas of Expertise Desired:
Drug Discovery, Research, Scientist, Senior Research Associate,

Job Description

Regulus Therapeutics Inc. (Nasdaq: RGLS) is a biopharmaceutical company located in San Diego, California leading the discovery and development of innovative medicines targeting microRNAs.

We are currently seeking an experienced drug discovery scientist to join our team at the Senior Research Associate (SRA) or Scientist level to advance our efforts in phenotypic screening for novel drug targets and compounds. For more information, visit

SRA / Scientist Discovery Research
Reference Code – 539

Position description and scope:

The successful candidate will be a member of a Drug Discovery Team Team and will provide important research experience and skills for the organization. Reporting to the Project Team Leader, the incumbent will be responsible for advancing new approaches for target identification and compound screening to expand the preclinical pipeline.  

Job responsibilities

1.   Perform in vitro and in vivo laboratory research within the specified Project Team, with an emphasis on establishing and developing phenotypic screening
2.   Design and conduct experiments under minimal supervision to generate high quality, reproducible results and critically analyze and interpret data
3.    Present clear data summaries at regularly scheduled Project Team meetings
4.   Perform parallel experimental work (multi-tasking) without compromise on data quality or reprodubility
5.   Document experimental protocols and results in an electronic laboratory notebook in accordance with company policy.


•   BA/BS in biology-related discipline (e.g. Cell Biology or Immunology) with a minimum of 6-8 years related laboratory experience (SRA Level)
•   PhD in biology related discipline (e.g. Cell Biology or Immunology) with a minimum of 2 years post-doctorate At least 2 years’ experience in a biotechnology or pharmaceutical industry drug discovery environment is required (Scientist Level)
•   Drug discovery experience in liver diseases a plus
•   Working knowledge specific cell type isolation from organs/tissues (e.g. liver) is highly desirable
•   Experience with in-vivo animal work in rodents to design in vivo experiments to support the Programs
•   Proficiency in basic computer data analysis and presentation applications: e.g. Microsoft Word, Excel, and PowerPoint

Techniques desired:

•   Experience in high content imaging and flow cytometry
•   Experience understanding of standard practices of cell and molecular biology including mammalian cell culture, cell transfection, RNA isolation, qPCR, cell-based functional assay development, ELISA
•   Experience in working with primary human cells and cellular assays is a plus

Personal Competencies:

•   Effective interpersonal skills, including both written and oral communication skills
•   Highly organized, Strong analytical skills, highly attentive to details, and strong work ethic
•   Ability to work within schedules and deadline
•   Team player, intensely committed to success and getting the job done well in a highly dynamic environment
•   Ability to multitask, prioritize, and function in a fast-paced entrepreneurial environment
•   Self-motivated, ability to work independently while also willing to follow protocols
•   Willingness to rapidly learn new laboratory and data analysis methods
•   Demonstrated ability to generate reproducible results, and to teach others

Regulus Therapeutics Inc. (Nasdaq: RGLS) is a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs.  Regulus has leveraged its oligonucleotide drug discovery and development expertise to develop a well-balanced microRNA therapeutics pipeline complemented by a rich intellectual property estate to retain its leadership in the microRNA field.  Regulus is advancing several programs in renal, hepatic and central nervous systems diseases.

Regulus is located in La Jolla, California and is led by a seasoned executive team experienced in corporate management, business, science, drug discovery and development. Regulus' scientific advisory board consists of world-class scientists and some of the foremost authorities in the field of microRNA research.

Excellent salary and benefits package offered.

You can visit our website to find out more about our company and culture:

Reference job code: 539


Regulus Therapeutics, Inc, is proud to be an EEO Employer.