Sr. Scientist, Assay Development - San Diego, CA | Biospace
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Sr. Scientist, Assay Development

Biological Dynamics

Location:
San Diego, CA
Posted Date:
9/5/2017
Position Type:
Full time
Job Code:
Salary:
Required Education:
Doctorate/PhD
Areas of Expertise Desired:
Assay Development, Biochemistry, Molecular Biology,

Job Description

Based in San Diego, CA, Biological Dynamics, Inc. (BioDyn) is a privately held molecular diagnostics company and a pioneer in the field of Alternating Current Electrokinetics (ACE)-based diagnostics.  At BioDyn, we are developing novel diagnostic solutions to screen, diagnose and manage high burden conditions, such as cancer. Our diverse team shares passion for improving patient care, a focus on cutting-edge technology, and a deep commitment to innovation, which shapes the future of our company and drives our innovative culture. To learn more about BioDyn, please visit our website, www.BiologicalDynamics.com, or feel free to view a TEDx Talk given by BioDyn’s Co-founder and CEO, Dr. Raj Krishnan, at https://www.youtube.com/watch?v=wMsOYqJ4ShA.

As part of our company’s commitment to developing and delivering to the market a suite of high-performance products, we are growing the Assay Development team.  One of our key open positions is for a Senior Scientist, Assay Development.   Candidates most suitable for this role will have a strong background in both biochemistry and molecular biology, ideally with experience in the development of assays, preferably molecular, for diagnostic use.  The individual in this hands-on role will design, perform, and analyze experiments as part of the development, verification, and validation of assays on BioDyn’s proprietary technology platform. This Scientist will also be responsible for performing complementary molecular assays, particularly quantitative PCR.  Importantly, the person in this role will apply creativity and novel approaches to solving problems and meeting challenges in the design and development of assays in close collaboration with hardware and software engineers, chemists, and material scientists.

Key Responsibilities:

•   Directly designs, performs, and analyzes experiments for assay development activities throughout feasibility, design, and development stages of the product development cycle;

•   Plays a key role in contributing to the identification and implementation of novel and improved assays in support of the company’s product development needs and in close collaboration with other key personnel in product development and engineering;

•   Develops and continuously improves a variety of molecular assays, with a particular focus on qPCR;

•   Identifies and provides creative and novel alternative approaches to meeting the challenges intrinsic to the development of the company’s products;

•   Leads and provides support, as necessary, to analytical studies and testing of clinical samples;

•   Contributes to the evaluation of new technologies and their application internally;

•   Partners effectively with other members of the Assay Development team as well as Engineering, Quality, Marketing, and all other groups in support of Product Development objectives;

•   Contributes on an as-needed basis to Design Reviews, Stage Gate meetings, and other processes required to advance through Design Control in support of IVD product development;

•   Effectively communicates experimental findings in written format and in internal company meetings; and

•   Other duties as assigned.

Requirements

•   Ph.D. in Biochemistry, Molecular Biology, Bioengineering or a closely related field, with a minimum of 2-4 years of industry experience.  Candidates with a Master’s degree and 7-10 years of industry experience may be considered;

•   Deep and extensive expertise in assay development, with a preference for molecular assays; complementary experience with immunoassays or biochemical assays preferred;

•   Knowledge of a variety of detection technologies, especially fluorescence-based assays and their use for nucleic acid quantification;

•   Experience in the development of molecular diagnostic products (US FDA 510k/PMA and CE mark) preferred, particularly with a focus on performing analytical studies;

•   Experience in working with cell-free DNA (cfDNA) in complex biological fluids such as plasma and knowledge of issues related to preparation and analysis of macromolecules in these contexts preferred;

•   Well versed in the use of standard statistical packages for data analysis;

•   Understands and applies risk management concepts in areas of direct responsibility; and

•   Strong verbal and written communication skills.

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.  While performing the duties of this job, the individual may be required to sit; use hands to touch, handle, or feel and reach with hands and arms. As well, s/he may occasionally be required to stand and/or move about the office or an event. Specific vision abilities may be required by this job including close vision and ability to adjust focus.

The successful candidate will join a dynamic, innovative team focused on developing cutting edge technologies in a fast-paced, collaborative environment. Biological Dynamics is an equal opportunity employer. We offer competitive compensation and benefits as well as a positive, diverse and exciting work environment.  To apply for this position please submit your cover letter and resume.