Senior Scientist, Protein Therapeutics - South San Francisco, CA | Biospace
Get Our FREE Industry eNewsletter

Senior Scientist, Protein Therapeutics

Pfizer Inc.

South San Francisco, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Masters Degree
Areas of Expertise Desired:

Job Description

About Pfizer

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Department Marketing Statement

Rinat is dedicated to developing new protein-based therapeutics to improve human life. Rinat researchers use the latest scientific knowledge and apply novel approaches to discover new ways of treating disease. Cooperation and support for a high level of scientific freedom is encouraged to find the best answers to biological questions. Rinat was formed in 2001 as an independent, private biotech company. In 2006, it was acquired by Pfizer, and is the biotechnology unit within Pfizer Worldwide Research & Development, dedicated to doing its part to fulfill Pfizer's mission of working together for a healthier world. Located in South San Francisco, California, Rinat provides the feel of a small company with the resources of a large pharmaceutical company in the heart of the biotech capital of the world.


The Protein Engineering Department is seeking an outstanding Senior Scientist to lead protein engineering and technology development projects. The candidate will be responsible for working closely with individuals in both protein engineering and immunology/oncology groups to innovate and develop the next generation of protein therapeutics for cancer treatment. The candidate will have access to state of the art protein and antibody engineering technologies and will be expected to continue our tradition of developing world class methods and technologies that enhance our therapeutic discovery efforts. The primary responsibilities include obtaining in-depth knowledge of the therapeutic targets of interest and using this information to formulate and design creative antibody/protein based therapeutics with high potential and new functionalities. This position requires the candidate to carry out hand-on lab work to apply protein engineering principles to generate novel protein therapeutics to target the immune system. The ideal candidate needs to have a strong understanding on how to engineer and characterize protein therapeutics. This work will also include close collaborations with biologists to design and evaluate different protein therapeutics of interest. The candidate needs to demonstrate strong desire and initiative to understand immunology and tumor biology, and help propose new ideas and techniques to discover next-generation therapeutics with unique functionalities.



* Ph.D. in Biological Science (Molecular Biology, Structural Biology, Protein Biochemistry, Cell Biology) or a related field (Chemical Engineering, Biomedical Engineering and Biological Engineering) * At least 2 years of post-graduate experience in either an academic or industrial setting is preferred
* Strong track record of scientific accomplishments demonstrated through publications in highly regarded journals and/or intellectual property generation.
* Track record of demonstrating analytical skills, creativity and unique problem solving skills
* Outstanding pro-active attitude, interpersonal, collaborative and oral communication skills
* Strong motivation, passion and commitment to science and engineering novel entities
* Ability and desire to work in an interdisciplinary scientific team and the desire to learn new techniques
* Ability to analyze and interpret work published in the field and apply it appropriately
* Technical expertise should include molecular biology and protein biochemistry, screening protein libraries, ELISA, biosensor, and/or other biochemical and cell based assays
* Prior experience in working with immune system derived proteins like antibody, TCR, cytokine and antibody-like scaffold proteins is preferred
* Previous experience with protein engineering techniques such as phage display and yeast display is preferred
* Prior experience in protein modeling and analyzing protein structures would be a plus
* Knowledge of translational work involving antibody and protein therapeutics in immunology and oncology would be of significant advantage

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.