Senior Scientist/Principal Scientist, Regenerative Respiratory Science, R&D - Gaithersburg, MD | Biospace
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Senior Scientist/Principal Scientist, Regenerative Respiratory Science, R&D

MedImmune, LLC

Gaithersburg, MD
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:

Job Description

Gaithersburg, Maryland, United States
Job reference: R-011802
Posted date: Aug. 08, 2017

If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us.

MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As a Senior Scientist or Principal Scientist, Regenerative Respiratory Science R&D, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.

We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.

MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.

The role:

We are seeking a candidate with a Ph.D. and/or, M.D./Ph.D degree who has a  broad understanding of the pathophysiological mechanisms underlying respiratory diseases, such as Chronic Obstructive Pulmonary Disease, Asthma and Idiopathc Pulmonary Fibrosis. This candidate would be expected to demonstrate a passion for innovative scientific research leading to the discovery and development of novel therapeutics. Expertise in areas of epithelial biology, stem cell biology and/or tissue regeneration and a strong scientific background, including high impact publications documenting original discoveries, is required. A background in human translational approaches to understand basic biological mechanisms and/or patient heterogeneity in disease is a plus but not essential.

The candidate will be responsible for leading innovative research and a small team of scientists focusing on tissue regeneration/stem cell biology in the lung. The candidate will inspire, develop, and critically evaluate research that results in novel discoveries and new therapies, while at the same time assuring close alignment with our colleagues in the UK and other stake holders. The ability to generate innovative discoveries for the development of novel biologic therapies, is essential.

Strong leadership and personal skills are required. The successful candidate should be able to work productively in a matrix team environment. Excellent written, oral, presentation and interpersonal skills are important.

Specific duties and major responsibilities include:

  • Serve as a scientific leader to ensure high scientific quality and consistent delivery of innovative discoveries. Lead and contribute to the success of the department’s goals for high impact publications.
  • Motivate and inspire a small group of talented scientists and postdoctoral fellows.
  • Drive productive research for the discovery of novel mechanisms of human disease, internally and in collaboration with leading external scientists.
  • Collaborate effectively with RIA scientists located in Cambridge, UK.
  • Represent RIA Research externally and in cross-functional, MedImmune-, and AstraZeneca-wide initiatives.
  • The position will be based in Gaithersburg, MD, USA.

Special Skills/Abilities:

  • Strong and inspirational leadership skills and the ability to work and lead in a matrix team environment.
  • Firm understanding of the mechanistic basis of human respiratory and other inflammatory diseases to drive novel discoveries and target evaluation.
  • Hands-on experience in basic research with a track record of novel discoveries and high impact publications, as well as an understanding of translational and clinical research.
  • Proficient in problem solving and the design of research strategy.
  • Outstanding verbal and written communication skills.



  • Ph.D. or M.D./Ph.D. or equivalent
  • Extensive experience in research with a significant leadership position in academia, industry, or a combination of these is required.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.