Senior Scientist, Medicinal Chemistry - Groton, CT | Biospace
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Senior Scientist, Medicinal Chemistry

Pfizer Inc.

Groton, CT
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:

Job Description

About Pfizer

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Role Description

We are seeking creative, enthusiastic, and highly motivated synthetic chemists to join our Pfizer Global Research and development laboratories based in Groton, CT. As part of a medicinal chemistry team, the successful applicants will contribute through innovative synthetic chemistry to the delivery of clinical candidates aligned against portfolio strategy.


* Contribute to the development and enablement of a coherent synthesis strategy associated to the project: understand the goal and medicinal chemistry strategy of the project and, as part of a synthesis team, positively and proactively influence and reduce to practice the strategy through development of innovative chemistry tailored to project needs.
* Development and enablement of versatile and modular synthetic routes compatible with rapid analog synthesis.
* Validation of these synthesis routes through reduction to practice via the synthesis of prototype molecules.
* Liaise with outsourcing point of contact in the team to ensure optimum transfer of the enabled chemistry to allow for rapid analog synthesis externally. Also, when applicable, be able to manage a pool of remotely located chemists assigned to analog synthesis.
* Develop scalable routes of preclinical candidates.
* Build effective partnerships with other lines, in particular analytical, technology, pharmaceutical sciences and process chemistry groups.
* Publish and present research internally and externally to Pfizer.



Educational Qualifications: - Doctoral level degree. Training and Experience: - Proven track record of creative thinking and consistent delivery as demonstrated by publication/presentation records. - Dual expertise in methodology development and successfully completed multistep syntheses. - Expertise in either organometallic chemistry, catalysis, peptide chemistry or chemical biology is recommended. - Postdoctoral experience strongly recommended. - Previous experience in mentoring and development of junior scientists or students is a plus. Competencies: - Highly skilled synthetic chemist in the area of methodology development and multistep synthesis. - Strong knowledge of techniques related to purification and characterization of organic compounds. - Effective communication and leadership skills; must be able to interact effectively within a multidisciplinary team of colleagues. - Comfortable working in a highly innovative environment and can effectively cope with change. -- Responds well to scientific challenge and applies significant rigor to their own work. - Will scientifically challenge others in their group in a constructive manner and demonstrate exceptional team working skills (e.g. approachable and collaborative) to ensure the group as a whole is successful. - Most astute reader of chemical literature. PHYSICAL/MENTAL REQUIREMENTS Requires the ability to carry out experimental organic chemistry in a standard chemistry laboratory.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.