Senior Scientist, DMPK - Novato, CA | Biospace
Get Our FREE Industry eNewsletter

Senior Scientist, DMPK

Ultragenyx Pharmaceutical Inc.

Apply
Location:
Novato, CA
Posted Date:
7/20/2017
Position Type:
Full time
Job Code:
Salary:
Required Education:
Doctorate/PhD
Areas of Expertise Desired:
DMPK, Senior Scientist,

Job Description

Why Join Us?

Ultragenyx is a clinical stage biotechnology company committed to bringing to market novel products for the treatment of rare and ultra-rare diseases with an initial focus on serious debilitating metabolic genetic diseases. Founded in 2010, the company has rapidly built a diverse portfolio of both large and small molecule candidates with the potential to address diseases for which the unmet medical need is high, the biology for treatment is clear, and for which there are no approved therapies.

Come join our team during this exciting time of growth and opportunities!

We are located in Novato, CA, 25 miles north of San Francisco with additional office space in Brisbane, California and Basel Switzerland. This position can be located in either Novato, CA or Brisbane, CA.

Position Summary

Ultragenyx is seeking a scientist II/senior scientist to join the DMPK group. The successful candidate is required to have solid training in pharmacokinetics and apply the knowledge and technical experience to address critical DMPK related issues to support drug discovery and development process in multi-disciplinary team setting.

Responsibilities, including but not limited to:

•     Evaluate in vitro-in vivo correlation in pre-clinical species to guide drug design and candidate selection
•     Design, conduct, interpretation and report PK and PK/PD experiments in pre-clinical species
•     Design and provide mechanistic interpretation for drug metabolism/transporter studies
•     Integrate pre-clinical data for human PK and dose prediction
•     Represent DMPK in project team
•     Prepare reports and documents for IND filings

Requirements

•     Ph.D. in pharmacokinetics/pharmaceutical sciences or related field with 2-5 years of experience; or MS with more than 8 years relevant industrial experience
•     Proficient with PK/PD data analysis and results interpretation
•     Experience with small molecules drug metabolism/transporter studies
•     Demonstrated leadership experience with project teams
•     Ability to design, conduct and report  in vitro and in vivo studies to address ADME related issues
•   Experience with therapeutic antibodies and/or oligonucleotides a plus
•   Excellent communication skills

Ultragenyx Pharmaceutical is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status.