Amgen is seeking a highly motivated Cell and Molecular Biologist to join the molecular biology group in Biologics Optimization at our state-of-the-art research facility at Amgen headquarters located in Thousand Oaks, CA. The Biologics Optimization group is a multidisciplinary team with capabilities in molecule design, cloning, expression and purification of therapeutic proteins. The group is responsible for the optimization, production, assessment, and selection of large molecule drug candidates.
The Senior Scientist will utilize their deep expertise in molecular biology, including vector design for recombinant protein expression and modern cloning techniques for the creation of complex multicomponent genetic constructs.
Independently design and engineer protein and expression constructs for diverse protein classes and expression hosts is desired.
Work with and have familiarity with automation and the ability to design high throughput work streams.
Act as a scientific leader with the ability to drive innovation, lead projects and teams, solve technical problems, and work independently and in cross-functional teams.
Develop innovative technologies to support the molecular cloning group, providing scientific results that support the generation of publications, patents, or regulatory submissions, and participating in internal and external scientific meetings.
Doctorate degree and 2 years of scientific experience within Biotech/Pharma industry
Master's degree and 5 years of scientific experience within Biotech/Pharma industry
Bachelor's degree and 7 years of scientific experience within Biotech/Pharma industry
Expertise with high throughput cloning processes and automated liquid handling platforms
Expertise in gene editing techniques
Strong knowledge of successful design strategies for mammalian and prokaryotic expression techniques
Strong communication and interpersonal skills, and the ability to work flexibly in a cross-functional team environment
Demonstrated track record of independent critical thinking and scientific achievement in research, exemplified by a strong publication or patent record
Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.
Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.