eNewsletter Signup
Miles
Km80.5

Senior Scientist / Associate Director of Pharmaceutics

Plexxikon Inc.

Apply
E-Mail to a Friend Add to Job Folder View All Jobs Back to Search Results Share
Location: Berkeley, CA Posted Date: 4/18/2013 Position Type: Full time Job Code: Senior Scientist Required Education: Doctorate/PhD Areas of Expertise Desired: Chemistry
Formulation

Description

Plexxikon is a leader in the discovery and development of novel, small molecule pharmaceuticals. The company has utilized its proprietary discovery platform to successfully develop a portfolio of competitively differentiated clinical and preclinical stage programs in a number of therapeutic areas. Plexxikon’s most advanced program, Zelboraf® (vemurafenib, and formerly known as PLX4032), was approved by the FDA in 2011 and is approved in over 60 countries worldwide. Plexxikon's demonstrated capability in discovery and early development uniquely positions the company to develop multiple commercial franchises for different therapeutic indications, and create significant value for Plexxikon and its collaborators.

Plexxikon's novel discovery approach, combined with an experienced management and scientific team, a broad network of scientific and clinical experts, and partnerships that support later stage development, have been key drivers of the company's success since it began operations in 2001.  In April 2011, Plexxikon became a member of the Daiichi Sankyo Group, and continues to build its broad and diverse pipeline and R & D operations independently.

Plexxikon is a small business with less than 50 employees and this position will be a critical member of the Non-Clinical Development team reporting to the Vice President of Non-Clinical Development.  This is an exceptional opportunity to gain experience in a successful biotech company.  

Responsibilities:
• Conducts formulation research and development activities with only general supervision.
• Determine possible causes of action, plan, schedule and execute laboratory activities to develop new pharmaceutical formulations to meet company objectives.
• Provides scientifically valid technical reports of work performed that may form the basis of regulatory submissions.
• Represents Formulation Development on multi-disciplinary project teams.
• Participates in technical transfer of formulation processes and data to contract manufacturing facilities and collaborators, including site visits.
• Interacts effectively with external areas e.g. drug discovery, manufacturing, external contractors and marketing to ensure timely project development.
• Supports several related or independent assignments at one time.
• Operates in compliance with all corporate, divisional and departmental HSE and quality directives.
• Report progress and results at group and project team meetings and attend weekly, company-wide research meetings  
• Document progress in electronic laboratory notebooks
• Work closely with other teams in the organization
• Lead the formulation team
• Other duties as assigned

Requirements

Position Requirements & Experience:
• PhD degree in Formulation, chemistry, or related field
• 10 or more years experience in an R&D or GMP laboratory setting
• ? Expertise in the production of a variety of successful solid and liquid formulations.
• Experience in the following procedures are desirable:  Particle size analysis, calorimetry, gravimetric analysis, microscopy, sieving, belnding/mixing, high shear mixing, wet/dry milling, extrusion, lyophilization, spray drying, etc.
• Ability to use standard instrumentations to perform formulation development related activities, interpret the data and present the results.
• Experience in adhering to cGMP principles and following SOPs.
• Must be able to successfully multi-task
• Desire to learn and tackle new challenges is imperative  
• Ability to interact closely and effectively with other researchers is necessary
• Excellent verbal and written communication skills are essential in this collaborative work environment

Plexxikon, an equal opportunity employer, is located in Berkeley, just off interstate 80.  We offer a chance to work with talented people in a collaborative environment and provide top-notch benefits including health insurance, generous time off and much more.   To learn more about Plexxikon, please visit our website at www.plexxikon.com.

All submissions will be evaluated and interviews will be conducted for those applicants who most strongly fit our needs. If you are not contacted for an interview, your resume will remain on file and active for available positions for a period of one year.

No Phone Calls  
No Agencies or Recruiters
Apply
E-Mail to a Friend Add to Job Folder



By applying to/saving a job using , you are agreeing to comply with and be subject to the Terms of Use for use of our website. To use our website, you must agree with the Terms of Use and both meet and comply with their provisions.

ADVERTISEMENTS