Senior Scientist - San Diego, CA | Biospace
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Senior Scientist

Metacrine, Inc.

San Diego, CA
Posted Date:
Position Type:
Full time
Job Code:
Required Education:
Areas of Expertise Desired:

Job Description

Job Description
Metacrine is a dynamic, driven small company headquartered in San Diego, CA. The company is focused on advancing novel molecules for treatment of metabolic diseases.  

We are looking for a highly motivated senior research scientist with drug discovery experience in diabetes and/or nonalcoholic steatohepatitis (NASH) and fibrosis.  The candidate will lead biology efforts on our type 2 diabetes program focused on a novel insulin sensitizer.  S/he will also play an active role in identify new drug targets for NASH and fibrosis.  Ideal candidate will have hands on experience with in vitro assays and animal models used to investigate efficacy of drug therapies and identify new drug targets.  S/he will work closely with protein engineering, chemistry, DMPK and biology group members to advancement projects from lead target identification to clinical candidate nomination.  


•   PhD in Biology or related field.
•   5-10 years drug discovery experience working in metabolic disease required.  
•   Hands on experience with in vivo and ex vivo biology, molecular and cell biology and assay development.  
•   Previous experience in managing direct reports
•   Strong written and verbal skills
•   Ability to work both collaboratively and independently; experience in start-up preferred
•   Experience in receptor tyrosine kinases a plus.
Please include cover letter highlighting relevant experience and expertise, all documents should be in PDF format.