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Senior Scientist

Isis Pharmaceuticals, Inc.

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Location: Carlsbad, CA Posted Date: 4/10/2013 Position Type: Full time Job Code: Req. 459 Salary: DOE Required Education: Doctorate/PhD Areas of Expertise Desired: Analytical Chemistry
Chemistry

Description

Isis Pharmaceuticals, Inc., located in the North San Diego County city of Carlsbad, was founded in 1989 to create advanced, novel medicines to treat complex and challenging diseases. We are the pioneer in the discovery and development of antisense drugs with more than 1600 patents.

Isis is a challenging, motivating and rewarding environment designed to foster innovation and scientific excellence. Our founding goals have changed little in over 20 years and our success is a direct result of our outstanding employees. We are interested in bringing together individuals with different skill sets into this creative environment to be part of a productive team.  Join us and experience our unique culture while you develop and expand your career.

SENIOR SCIENTIST, MEDICINAL CHEMISTRY

RESPONSIBILITIES:
We are looking for a motivated individual to join our Medicinal Chemistry group. Candidate will design and execute multi-step synthesis to prepare novel nucleosides and incorporate them into oligonucleotides using standard automated solid-phase chemistry, and will perform all other duties as assigned.

Requirements

•Possess a Ph.D. in Organic/Medicinal/Nucleic acid Chemistry
•Possess 0-5 years post-doctoral experience in academia or industry
•Experience with automated lab equipment
•A track record of scientific productivity as evidenced by high quality publications and/or patents
•An ability to plan and execute multi-step synthesis
•Be experienced in modern chromatographic and analytical techniques like TLC, column chromatography, HPLC and NMR to purify and characterize organic compounds
•Knowledge of nucleoside/oligonucleotide synthesis is a plus
•An ability to be productive and successful in an intense work environment

Excellent salary and benefits package offered.

For more information on Isis and to apply for this position, please visit our website, www.isispharm.com.  Reference Requisition #459

NO PHONE CALLS PLEASE.  PRINCIPALS ONLY.

Isis Pharmaceuticals, Inc. is proud to be an EEO employer.
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