Located in Boston, the Center for Immuno-Oncology (CIO) of the Dana-Farber Cancer Institute (DFCI) brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer through novel immune-based therapies.
Performs professional work in support of scientific research utilizing biopsy samples obtained from patients receiving immuno-therapy. Under general supervision, assists in determining the most suitable methods to be used in research; independently performs scientific investigative procedures requiring application of professional judgment and technology; interprets results and determines whether they are consistent with experimental goals; reviews literature; assists in the assembly, organization and interpretation of data.
Performs technical procedures such as immunohistochemistry, immunofluorescence, fluorescent in-situ hybridization, electrophoresis or other assays; prepares materials for microscopic examination.
- Performs procedures involving isolation and quantification of nucleic acids such as isolation of DNA and RNA from fresh and fixed tissues.
- Prepares and processes blood and tissue specimens from human subjects.
- Operates instruments and equipment such as spectrophotometer, scintillation counters, centrifuges, nucleic acid quantification (nanodrop), incubators, and light microscopes.
- Operates ancillary equipment such as photographic equipment and computer equipment.
- Under the PI supervision, performs evaluation of immmunohistochemistry and immunofluorescence stains utilizing computer-based image analysis systems.
- Manages and maintains database containing experimental results and reagent information and storage locations
- Conducts literature reviews to assist in determining most suitable methods to be used in research.
- Prepares and presents written or oral progress reports concerning studies, including assembly, organization and interpretation of data.
- Performs statistical analysis of data.
- Prepares laboratory reagents, chemicals, instruments and equipment.
- Orders chemicals, reagents and other laboratory supplies.
- Performs routine maintenance and minor repairs of laboratory apparatus and instruments.
- Maintains a clean, orderly work area within the laboratory.
- Undertakes standard decontamination procedures prior to disposal of certain laboratory materials.
- Functions as the laboratory safety officer, responsible for compliance with all regulatory requirements, and the safe use of hazardous materials in the laboratory, including radioactive, biological and chemical agents.
- May assist in supervising the work of other assigned laboratory personnel.
- May demonstrate and explain various laboratory techniques to laboratory personnel, students and others.
- Maintains established department policies, procedures and objectives, including the areas of quality assurance, safety, environmental and infection control.
- Performs all other duties and responsibilities as directed.
- Master's Degree required with a major in biology or chemistry preferred.
- Immunohistochemistry experience is required.
- Minimum of 2-4 years related experience.
- Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.
- Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
- Ability to analyze information and use logic to address work-related issues and problems.
- Must have attention to detail and be thorough in completing work tasks.
- Ability to work within a team environment.
Desired skills but not obligatory: Experience with histomorphology and experience with image analysis/morphometry software.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.