Senior Research Associate / Scientist - Menlo Park, CA | Biospace
Get Our FREE Industry eNewsletter

Senior Research Associate / Scientist

Adicet Bio, Inc.

Location:
Menlo Park, CA
Posted Date:
8/22/2017
Position Type:
Full time
Job Code:
Salary:
Required Education:
Masters Degree
Areas of Expertise Desired:
Scientist, Senior Research Associate,

Job Description


We are seeking a highly-motivated candidate with a strong basic research background in cell biology.  This position requires expertise in primary cell tissue culture, and a demonstrated ability to monitor protein-protein interactions within cells, changes in protein expression levels, and post-translational modifications (e.g. phosphorylation, ubiquitination).  Expertise in flow cytometry, western blotting, and ELISA are a must.  The successful candidate will work as a part of a multidisciplinary team, utilizing the latest technologies for cell engineering and contributing to the generation of novel cell based therapeutics for the treatment of cancer.

Company

Adicet bio, Inc. is a privately held, preclinical stage biotechnology company that is engaged in the development of cutting-edge immunotherapies for cancer and other disease indications, with a focus on novel universal immune cell therapies. Adicet’s immune cell platform is complemented by expertise of its wholly owned subsidiary, Adicet Bio Israel Ltd., which identifies and validates novel disease specific peptide-MHC targets and generates T cell receptor-like antibodies that can be used to specifically target immune cells to diseased cells.

Adicet Bio was founded in late 2015 and closed a Series A financing of $51M in Jan 2016. This financing was led by OrbiMed and also included Novartis Venture Funds and Pontifax. In August 2016, Regeneron and Adicet Bio announced a strategic collaboration to discover and develop next-generation engineered immune-cell therapeutics, for which Adicet received a $25M upfront payment.
In September 2016, Adicet Bio was recognized and named by FierceBiotech to its “Fierce 15” Biotech Companies of 2016.

Job Responsibilities

Perform research activities including isolation of PBMCs, assay development, immunoprecipitation, western blotting, flow cytometry, and ELISA to support the Adicet Bio Immunology Group.  Analyze data and summarize for presentation to the team.  

Requirements


- MS or PhD in biological sciences or a related field
- 5+ years of relevant academic and industry experience in cell biology, cellular immunology, molecular biology, stem cell biology
- Demonstrated proficiency to work aseptically in tissue culture
- Hands on experience in primary cell culture, cell-based assay, immunoassay, western blotting and flow cytometry are required
- Experience in multi-parameter/multi-color flow cytometry is preferred
- Experience with handling of human biological specimens, particularly blood, isolation of PBMC using density gradient centrifugation (Ficolling). Separation of B, T and NK cells by cell enrichment and depletion using magnetic beads, or sorting
- Experience with data processing software such as GraphPad Prism, FlowJo or similar is required
- Ability to work independently, multitask and meet deadlines in a fast-paced environment
- Highly motivated, organized and disciplined record keeping
- Exceptional verbal and written communication skills